TABLE 3.

Secretion of pertussis toxin after 24 h

Treatment group	Amt of toxin secreted (ng/ml)a
	Control	Treated
BPM3171 (secretion mutant)	24.2 ± 4.2*	NDb
Wild-type BP338 (control versus treated)
Erythromycin	936 ± 180	150 ± 29*
Chloramphenicol	936 ± 180	175 ± 25*
Rifampin	1,560 ± 540	175 ± 83*
Piperacillin	1,830 ± 278	250 ± 0*
Cefoperazone	1,830 ± 278	333 ± 53*
Polymyxin B (50 μg/ml)	1,410 ± 345	80.2 ± 29*
Polymyxin B (25 μg/ml)	1,248 ± 279	116 ± 17*
Ethanol	2,251 ± 155	187 ± 43*
Lidocaine	1,502 ± 159	70 ± 14*
Procaine	1,445 ± 261	34 ± 6.0*

^aAmount of pertussis toxin secreted in 24 h from secretion mutant BPM3171 or wild-type BP338 treated as indicated. *, values statistically significantly different from control BP338 values (P < 0.05). 

^bND, not determined.