. 2022 Mar 24;10:664261. doi: 10.3389/fcell.2022.664261

TABLE 2.

Summary of characteristic markers of mouse and human hematopoietic cell population.

Cell type	Mouse markers	Human markers	PMID
Hematopoietic stem cells (HSCs)	Lin⁻c-Kit⁺Sca1⁺Flk2⁻CD34⁻Slamf1⁺	Lin⁻CD34⁺CD38⁻CD90⁺CD45RA⁻	20890962
Long-term HSCs (LT-HSCs)	Lin⁻c-Kit⁺Scal⁺Flt3⁻CD34⁻CD150⁺Thy1.1^+/low	Lin⁻CD34⁺CD38⁻CD45RA⁻CD90⁺	31230184
	—	Lin⁻CD34⁺CD38⁻CD45RA⁻CD90⁺CD49f⁺	21737740
	—	CD34⁺CD45RA⁻ITGA3⁺EPCR⁺CD90⁺	31340144
Short-term HSCs (ST-HSCs)	Lin⁻c-Kit⁺Sca1⁺Flt3⁻ CD34⁺CD150⁺Thy1.1^+/lowMac-1^low	—	31230184
	—	Lin⁻CD34⁺CD38⁻CD45RA⁻CD90⁻CD49f⁻	21737740
	—	CD34⁺CD45RA⁻ITGA3⁻EPCR⁺CD90⁺	31340144
Multipotent progenitors (MPPs)	Lin⁻c-Kit⁺Sca1⁺Flk2⁻CD34⁺Slamf1⁺	Lin⁻CD34⁺CD38⁻CD90⁻CD45RA⁻	20890962
Common lymphoid progenitors (CLP)	Lin⁻Flk2⁺IL7RA⁺CD27⁺	Lin⁻CD34⁺CD38⁺CD10⁺	20890962
Common myeloid progenitor (CMP)	Lin⁻c-Kit⁺Sca1^−/lowCD34⁺FcgR^low	Lin⁻CD34⁺CD38⁺IL3RA^lowCD45RA⁻	20890962
Megakaryocyte-erythrocyte progenitors (MEP)	Lin⁻c-Kit⁺Sca1⁻CD34⁻FcgR⁻	Lin⁻CD34⁺CD38⁺IL3Ra⁻CD45RA⁻	20890962
Granulocyte-macrophage progenitors (GMP)	Lin⁻c-Kit⁺Sca1⁻CD34⁺FcgR⁺	Lin⁻CD34⁺CD38⁺IL3Ra⁺CD45RA⁻	20890962

CD: cluster of differentiation; CLP: common lymphoid progenitors; CMP: common myeloid progenitors; EPCR: Endothelial Protein C Receptor; FcgR: Fragment of IgG receptor; Flk2: Fetal liver kinase 2; Flt3: FMS-like tyrosine kinase 3; GMP: Granulocyte-Macrophage Progenitors; HSC: hematopoietic stem cell; ITGA: Integrin Subunit α-1; Lin: Lineage; LT-HSC: Long-Term Hematopoietic Stem Cell; Mac-1: Macrophage-1, antigen; MEP: Megakaryocyte-Erythrocyte Progenitors; MPP: multipotent progenitors; Sca1: Stem Cell Antigen 1; Slamf1: Signalling lymphocytic activation molecule family member 1; ST-HSC: Short-Term Hematopoietic Stem Cell.