Table 1A.
Clinical and imaging data of MOGAD patients.
| # | Myelitis | ON | EDSS | Number of relapses | Number of relapses before MRI | Brain MRI | Disease duration (months) | Duration from first episode to MRI (months) | Treatment | OCB |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | No | BIL ON | 1 | 2 | 2 | Encephalitis-likea | 48 | 30 | B-cell depletion | Negative |
| 2 | No | Uni ON | 1 | 2 | 1 | Normal | 30 | 11 | Prednisone | Positive |
| 3 | Yes | Uni ON | 0 | 3 | 2 | NMO-likeb | 42 | 11 | Methotrexate | Negative |
| 4 | Yes | No | 0 | 1 | 1 | Normal | 36 | 3 | No Treatment | Negative |
| 5 | No | BIL ON | 2 | 4 | 2 | MS-likec | 24 | 12 | B-cell depletion | Positive |
| 6 | No | No | 0 | 1 | 1 | Non-specific lesionsd | 18 | 18 | No Treatment | Positive |
| 7 | Yes | No | 5 | 1 | 1 | Normal | 72 | 58 | No Treatment | Negative |
| 8 | Yes | Uni ON | 4 | 2 | 2 | Normal | 18 | 11 | No Treatment | Negative |
| 9 | No | Uni ON | 1 | 1 | 1 | Normal | 42 | 9 | No Treatment | Negative |
| 10 | Yes | No | 1 | 1 | 1 | Normal | 54 | 33 | No Treatment | Negative |
| 11 | No | BIL ON | 1 | 2 | 1 | Non-specific lesionse | 30 | 6 | Prednisone | Negative |
| 12 | No | BIL ON | 1 | 1 | 1 | NMO-likef | 132 | 84 | No Treatment | NA |
| 13 | No | BIL ON | 0 | 1 | 1 | Normal | 30 | At first episode | No Treatment | Negative |
| 14 | No | Uni ON | 1 | 2 | 2 | Normal | 120 | 120 | B-cell depletion Prednisone | NA |
| 15 | Yes | No | 0 | 1 | 1 | Area postrema lesion | 42 | 11 | No Treatment | NA |
| 16 | No | Uni ON | 0 | 4 | 4 | Normal | 132 | 96 | Cellcept | NA |
| 17 | No | BIL ON | 1 | 1 | 1 | Normal | 8 | At first episode | No Treatment | Negative |
| 18 | No | Uni ON | 1 | 1 | 1 | Normal | 5 | At first episode | No Treatment | Negative |
| 19 | No | Uni ON | 2 | 1 | 1 | Normal | 5 | At first episode | No Treatment | Negative |
| 20 | No | Uni ON | 0 | 1 | 1 | Normal | 4 | At first episode | No Treatment | Negative |
| 21 | Yes | No | 2 | 1 | 1 | Normal | 3 | At first episode | No Treatment | Positive |
| 22 | No | Uni ON | 0 | 1 | 1 | Normal | 108 | At first episode | No Treatment | Negative |
Uni ON, unilateral optic neuritis; BIL ON, bilateral optic neuritis; NMO, neuromyelitis optica; OCB, oligoclonal bands; NA, data not aviable; EDSS, estimated disability status scale.
aProlongation of MRI signal at frontal, parietal and temporal cortex. In addition, prolongation of MRI signal in pons and brain stem.
bAbnormal signal intensity involving the medulla and pons.
cMultiple white matter lesion within the white matter of the cerebral hemispheres. One lession located in the periventricular white matter of the occipital lobe.
dMultiple bilateral hyperintense non-enhancing T2/Flair Foci involving the supratentorial periventricular and centrum locations.
eNon-specific lesions at subcortical frontal white matter.
fProlongation of T2/Flair in subcortical supratentorial deep white matter.