Table 1.
Baseline characteristics of the study population and comparative analysis between patients with co-sensitization to mite and shrimp and those sensitized only to mites.
| Control group |
All HDM allergic patient | Shrimp sensitization |
|||
|---|---|---|---|---|---|
| HDM allergy and Shrimp - | HDM allergy and Shrimp + | p | |||
| Number of patients | 126 | 446 | 335/466 (79,6%) | 91/466 (20,4%) | / |
| Age, years, mean ± SD [range] | 23,3 ± 10,8 [4-73] | 21,7 ± 14,5 [0,6–74] | 21,4 ± 14,6 | 23,1 ± 14,3 | 0,190 |
| Gender | 0,579 | ||||
| Males, % (n/N) | 46,8% (59/126) | 46,9% (209/446) | 46,2% (164/355) | 49,5% (45/91) | |
| Females, % (n/N) | 53,2% (67/126) | 53,1% (237/446) | 53,8% (191/355) | 50,5% (46/91) | |
| HDM related symptoms | |||||
| Asthma, % (n/N) | 47,6% (60/126) | 43,7% (195/446) | 40,6% (144/355) | 56% (51/91) | 0,008 |
| Rhinitis, % (n/N) | 63,5% (80/126) | 61% (272/446) | 59,4% (211/355) | 67% (61/91) | 0,185 |
| Co-sensitization aeroallergens, % (n/N) | na | 38,3% (171/446) | 38,3% (136/355) | 38,5% (35/91) | 0,979 |
| Co-sensitization food allergensa, % (n/N) | na | 07% (31/446) | 6,2% (22/355) | 9,9% (9/91) | 0,217 |
| Der p sensitization | |||||
| % (n/N) | 0% (0/126) | 98,7% (440/446) | 98,3% (349/355) | 100% (91/91) | 0,607 |
| sIgE level (kU/l) | na | 27,8 (4,7–84,4) | 22,3 (3,7–70,4) | 62,2 (20,6–142) | <0,001 |
| Der f sensitization | |||||
| % (n/N) | 0% (0/126) | 94,2% (420/446) | 92,7% (329/355) | 100% (91/91) | 0,004 |
| sIgE level (kU/l) | na | 17,3 (2,9–56,3) | 12,9 (2,1–42,6) | 49 (16,4–96,9) | <0,001 |
Data are presented as medians and inter-quartiles (Q1-Q3) or % (n/N) (%), where N is the total number of patients. p values comparing patients with and without shrimp sensitization are from Mann-Whitney U test, χ2 test or Ficher's exact test as appropriate. na: not available.
a
Others than shellfish