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. 2022 Mar;11(3):381–392. doi: 10.21037/tlcr-22-168

Figure 3.

Figure 3

Clinical course of recurrence of CIP. Individual clinical courses of patients with pneumonitis, from initiation of ICIs therapy, the first episode of CIP, the recurrence of CIP, to last follow-up or death. In most patients, there is sufficient follow-up time that minimizes the possibility of the recurrence of pneumonitis. The median onset of CIP for patients without recurrence and with recurrence was 3.49 months (IQR, 0.26–31.93 months) and 2.78 months (IQR, 1.22–20.93 months), respectively. The median interval duration between initial and recurrent CIP was 1.54 months (IQR, 0.98–20.93 months). CIP, checkpoint inhibitor-related pneumonitis; ICIs, immune checkpoint inhibitors; MP, methylprednisolone; IQR, interquartile range.