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EC50 (µM) summary table of APX3330, APX2009, APX2014 cytotoxicity assays in KC3590 lines.
| EC50 µM | Parent | Vector | C13 | C15 |
|---|---|---|---|---|
| APX3330 | 60.8 (± 1.5) | 52.9 (± 5.3) | *36.2 (± 2.3) | *39.3 (± 5.7) |
| APX2009 | 16.8 (± 1.9) | 13.7 (± 1.1) | ***##6.6 (± 0.1) | **##6.6 (± 0.2) |
| APX2014 | 6.0 (±0.3) | 6.0 (±0.9) | ***###3.0 (± 0.1) | ***###2.8 (± 0.4) |
*p < 0.05, **p < 0.001, ***p < 0.0001 vs Parent line; ##p < 0.001, ###p < 0.0001 vs Vector line, One-way ANOVA (N = 3).
