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. 2022 Mar 24;12:817692. doi: 10.3389/fonc.2022.817692

Figure 1.

Figure 1

Pathological Response Patterns Following Neoadjuvant Chemoradiotherapy. (A) No/minimal tumor regression, vital tumor cells, and prominent keratin pearls; (B) Tumor fragmentation with increased amount of fibrous connective tissue with scattered groups of vital tumor cells; (C) Tumor shrinkage with a solitary group of vital tumor cells embedded in fibrous connective tissue; (D) Complete response with no vital tumor cells within fibrous connective tissue; salivary glands, and skeletal muscles located on the right.