Figure 1.

Physiological parameters of C57BL/6J, C57BL/6N, and NMRI mice. (A) Nose-to-tail length. (B) Body mass. (C) Body mass index calculated as the ratio between body weight and body surface area (g/m²). (D) Non-fasting glucose concentration. Data for panels A-D were obtained from 8 C57BL/6J, 6 C57BL/6N, and 6 NMRI mice. (E) Representative islet of Langerhans. The islet border is marked with a red line. (F) Islet cross-section area in the pancreas tissue slice (median values 38 373 μm² vs. 51 267 μm² vs. 56 861 μm² for C57BL/6J, C57BL/6N, and NMRI, respectively) obtained from 63/7, 64/6, 75/6 islets/mice from C57BL/6J, C57BL/6N, and NMRI mice respectively. Where present, the following symbols in indicate p-values: *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; ns, not significant.