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VISTA-/- mice have significantly higher levels of several Th17 cytokines following septic challenge. (A–J) Plasma cytokine concentration of wild-type and VISTA-/- mice. Summary graphs show mean ± SEM [WT-sham: n = 5, WT-CLP: n = 5, VISTA-/-sham: n = 5, VISTA-/- -CLP: n=5]; significance #p = 0.05; *p < 0.05; **p < 0.01; ****p < 0.0001.
