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Time-kill curve for approximately 106 MRSA bacteria (oxacillin MIC, 24 μg/ml; vancomycin MIC, 1 μg/ml), in the presence of no antibiotics (▴), 0.5 μg of vancomycin (■) per ml, 8 μg of oxacillin (●) per ml, and 0.5 μg of vancomycin plus 8 μg of oxacillin (⧫) per ml. All agents were readministered at 6 h (∧). E, exponential log10.
