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. 2022 Feb 22;14(4):e15344. doi: 10.15252/emmm.202115344

Figure 7. IRE1‐FMRP signaling controls cholesterol efflux and efferocytosis pathways in macrophages.

Figure 7

IRE1‐mediated FMRP phosphorylation suppresses translation of mRNA for key cholesterol transporters and efferocytosis receptors in macrophages and promotes atherosclerosis.