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. 2022 Mar 24;13:803121. doi: 10.3389/fmicb.2022.803121

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Copyright © 2022 Aguilera, Mascardi, Belforte, Rosso, Quesada, Llovet, Iraola, Trinks and Penas-Steinhardt.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of the microbiome community of PPG and PG groups. Alpha Diversity measures: Observed features (A), Shannon index on a base-2 logarithmic scale (B) and Faith phylogenetic diversity (C). *p = 0.026; ^*⁣*⁣**p < 0.001. Rarefaction curves of the samples from the PPG and PG (D). The x axis represents the number of sequences sampled while the y axis represents a measure of the species richness detected (estimated number of observed features). The red vertical dotted line represents the rarefaction depth chosen (sample with the least amount of sequences). PCoA plots of beta diversity with weighted (E) and unweighted (F) UniFrac distances, respectively. Ellipses represent the 95% confidence interval of each group. Colors are assigned by group, red for PPG and blue for PG.