TABLE 1.

Small and large HSPs involved in diseases.

1	S	Name	Disease	References
2	Small HSPs	HSP27	Colorectal cancer; breast cancer; oral tongue squamous cell carcinoma	Wang et al. (2009), Yu et al. (2010), Thuringer et al. (2015), Wang et al. (2020)
3		α-Crystallins	Tumors; neurodegenerative diseases; ocular diseases	Renkawek et al. (1994), Dimberg et al. (2008), Kase et al. (2011)
4		HSP70	Lung cancer; acute myeloid; leukemia; colorectal cancer; gastric cancer	Kocsis et al. (2010), Lee et al. (2013), Piszcz et al. (2014)
5		HSP90	Lung adenocarcinoma; esophageal squamous cell carcinoma; breast cancer	Park et al. (2015), Xu et al. (2016), Moyano et al. (2021)
6	Large HSPs	HSP110	Brain ischemia, kainic acid-dependent cell injury, cerebellar Purkinje cell degeneration	Ni and Lee (2007), Sokka et al. (2007), Su and Li (2016)