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. 2022 Apr 7;19:83. doi: 10.1186/s12974-022-02447-5

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Immune landscape in the post-stroke aged brain revealed by scRNA-seq. A Changes in the frequency of major cell types in the aged brain on day 3 after stroke. B Volcano plots and the top 20 enriched gene ontology terms of biologic process for MG5 vs MG1 and Neut1 vs Neut2. C UMAP plots depicting expression of selected genes in the stroke aged brain