| 1 Recovery time |
11 |
776 |
Mean Difference (IV, Random, 95% CI) |
‐16.59 [‐24.99, ‐8.18] |
| 1.1 Propofol alone |
4 |
249 |
Mean Difference (IV, Random, 95% CI) |
‐14.68 [‐19.79, ‐9.58] |
| 1.2 Propofol combined with another agent |
7 |
527 |
Mean Difference (IV, Random, 95% CI) |
‐17.36 [‐29.39, ‐5.34] |
| 2 Recovery time (minutes) in studies, which reported recovery time in formats which could not be meta‐analyzyed |
|
|
Other data |
No numeric data |
| 3 Discharge time |
7 |
542 |
Mean Difference (IV, Random, 95% CI) |
‐20.86 [‐30.94, ‐10.78] |
| 3.1 Propofol alone |
4 |
297 |
Mean Difference (IV, Random, 95% CI) |
‐19.06 [‐28.08, ‐10.04] |
| 3.2 Propofol combined with another agent |
3 |
245 |
Mean Difference (IV, Random, 95% CI) |
‐32.17 [‐64.84, 0.50] |
| 4 Procedure duration |
9 |
736 |
Mean Difference (IV, Random, 95% CI) |
0.84 [‐1.02, 2.71] |
| 4.1 Propofol alone |
2 |
168 |
Mean Difference (IV, Random, 95% CI) |
‐1.98 [‐6.12, 2.17] |
| 4.2 Propofol combined with another agent |
7 |
568 |
Mean Difference (IV, Random, 95% CI) |
1.85 [‐0.26, 3.97] |
| 5 Cecal intubation |
9 |
1840 |
Odds Ratio (M‐H, Random, 95% CI) |
0.41 [0.22, 0.76] |
| 5.1 Propofol alone |
3 |
268 |
Odds Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 5.2 Propofol combined with another agent |
6 |
1572 |
Odds Ratio (M‐H, Random, 95% CI) |
0.41 [0.22, 0.76] |
| 6 Patient Dissatisfication (dichotomous data) |
6 |
449 |
Odds Ratio (M‐H, Random, 95% CI) |
0.22 [0.11, 0.44] |
| 6.1 Propofol alone |
2 |
117 |
Odds Ratio (M‐H, Random, 95% CI) |
0.25 [0.09, 0.72] |
| 6.2 Propofol combined with another agent |
4 |
332 |
Odds Ratio (M‐H, Random, 95% CI) |
0.19 [0.07, 0.50] |
| 7 Patient Satisfication (continuous data) |
4 |
370 |
Std. Mean Difference (IV, Random, 95% CI) |
0.43 [‐0.00, 0.85] |
| 7.1 Propofol alone |
3 |
220 |
Std. Mean Difference (IV, Random, 95% CI) |
0.50 [‐0.17, 1.17] |
| 7.2 Propofol combined with another agent |
1 |
150 |
Std. Mean Difference (IV, Random, 95% CI) |
0.32 [‐0.02, 0.66] |
| 8 Patient Dissatisfication (combined) |
7 |
|
Odds Ratio (Random, 95% CI) |
0.35 [0.23, 0.53] |
| 8.1 Propofol Alone |
4 |
|
Odds Ratio (Random, 95% CI) |
0.33 [0.18, 0.60] |
| 8.2 Propofol combined with another agent |
3 |
|
Odds Ratio (Random, 95% CI) |
0.33 [0.14, 0.80] |
| 9 Pain Control (continuous outcome) |
6 |
633 |
Std. Mean Difference (IV, Random, 95% CI) |
0.38 [0.03, 0.74] |
| 9.1 Propofol alone |
2 |
187 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.14 [‐0.53, 0.26] |
| 9.2 Propofol combined with another agent |
4 |
446 |
Std. Mean Difference (IV, Random, 95% CI) |
0.51 [0.17, 0.84] |
| 10 Pain Control (dichotomous outcome) |
5 |
344 |
Odds Ratio (M‐H, Random, 95% CI) |
1.12 [0.21, 5.97] |
| 10.1 Propofol alone |
3 |
220 |
Odds Ratio (M‐H, Random, 95% CI) |
0.20 [0.02, 1.79] |
| 10.2 Propofol combined with another agent |
2 |
124 |
Odds Ratio (M‐H, Random, 95% CI) |
2.64 [0.39, 18.04] |
| 11 Pain Control (combined) |
9 |
|
Odds Ratios (Random, 95% CI) |
1.71 [1.02, 2.88] |
| 11.1 Propofol Alone |
3 |
|
Odds Ratios (Random, 95% CI) |
0.67 [0.34, 1.33] |
| 11.2 Propofol combined with another agent |
6 |
|
Odds Ratios (Random, 95% CI) |
2.27 [1.42, 3.63] |
| 12 Hypoxia |
15 |
1408 |
Odds Ratio (M‐H, Random, 95% CI) |
0.80 [0.48, 1.31] |
| 12.1 Propofol alone |
5 |
407 |
Odds Ratio (M‐H, Random, 95% CI) |
0.69 [0.25, 1.89] |
| 12.2 Propofol combined with another agent |
10 |
1001 |
Odds Ratio (M‐H, Random, 95% CI) |
0.83 [0.47, 1.48] |
| 13 Apnea |
11 |
918 |
Odds Ratio (M‐H, Random, 95% CI) |
1.35 [0.56, 3.24] |
| 13.1 Propofol alone |
5 |
407 |
Odds Ratio (M‐H, Random, 95% CI) |
1.35 [0.56, 3.24] |
| 13.2 Propofol combined with another agent |
6 |
511 |
Odds Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 14 Respiratory depression requiring intervention |
10 |
898 |
Odds Ratio (M‐H, Random, 95% CI) |
0.67 [0.15, 2.89] |
| 14.1 Propofol alone |
3 |
268 |
Odds Ratio (M‐H, Random, 95% CI) |
0.33 [0.01, 8.21] |
| 14.2 Propofol combined with another agent |
7 |
630 |
Odds Ratio (M‐H, Random, 95% CI) |
0.81 [0.16, 4.18] |
| 15 Arrhythmias |
7 |
684 |
Odds Ratio (M‐H, Random, 95% CI) |
0.70 [0.31, 1.55] |
| 15.1 Propofol alone |
3 |
220 |
Odds Ratio (M‐H, Random, 95% CI) |
0.55 [0.09, 3.46] |
| 15.2 Propofol combined with another agent |
4 |
464 |
Odds Ratio (M‐H, Random, 95% CI) |
0.74 [0.30, 1.80] |
| 16 Hypotension |
6 |
548 |
Odds Ratio (M‐H, Random, 95% CI) |
0.97 [0.55, 1.71] |
| 16.1 Propofol alone |
2 |
144 |
Odds Ratio (M‐H, Random, 95% CI) |
1.03 [0.28, 3.83] |
| 16.2 Propofol combined with another agent |
4 |
404 |
Odds Ratio (M‐H, Random, 95% CI) |
0.96 [0.51, 1.79] |
| 17 Blood pressure drop or lowest blood pressure during the procedure |
5 |
494 |
Mean Difference (IV, Random, 95% CI) |
2.19 [‐2.55, 6.94] |
| 17.1 Propofol alone |
2 |
199 |
Mean Difference (IV, Random, 95% CI) |
0.45 [‐9.40, 10.30] |
| 17.2 Propofol combined with another agent |
3 |
295 |
Mean Difference (IV, Random, 95% CI) |
3.63 [‐4.47, 11.72] |
| 18 Colonic perforations |
1 |
7286 |
Odds Ratio (M‐H, Random, 95% CI) |
2.87 [0.60, 13.83] |
| 18.1 Propofol alone |
1 |
7286 |
Odds Ratio (M‐H, Random, 95% CI) |
2.87 [0.60, 13.83] |
| 18.2 Propofol combined with another agent |
0 |
0 |
Odds Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 19 Sedation (failure to sedate) |
2 |
277 |
Odds Ratio (M‐H, Random, 95% CI) |
0.03 [0.00, 1.43] |
| 19.1 Propofol alone |
1 |
99 |
Odds Ratio (M‐H, Random, 95% CI) |
0.20 [0.07, 0.60] |
| 19.2 Propofol combined with another agent |
1 |
178 |
Odds Ratio (M‐H, Random, 95% CI) |
0.00 [0.00, 0.01] |
| 20 Sedation |
6 |
521 |
Std. Mean Difference (IV, Random, 95% CI) |
0.41 [‐0.45, 1.27] |
| 20.1 Propofol alone |
3 |
268 |
Std. Mean Difference (IV, Random, 95% CI) |
1.38 [0.93, 1.82] |
| 20.2 Propofol combined with another agent |
3 |
253 |
Std. Mean Difference (IV, Random, 95% CI) |
‐0.53 [‐0.98, ‐0.09] |
