Figure 5.
Nanodrop imaging in chicken embryos. (a) B-mode ultrasound image of chicken embryo imaged through the intact skull, with ADV nanodrops visible as bright spots. (b) Position of the vessel-relative position of nanodrops could be isolated in this imaging data set via singular value decomposition (SVD)-based filtering to extract stationary features. (c) SVD clutter filtering was used to generate ultrasound microvessel images. Arrows point to ADV nanodrops. (d) B-mode ultrasound image of the chorioallantoic membrane (CAM). (e) ADV nanodrop signals isolated using SVD filtering. (f) Nanodrop signals overlaid onto ultrasound microvessel perfusion images of CAM vasculature.