Kalmeijer 2002.

Methods	Double‐blind, randomised controlled trial
Participants	Orthopedic surgery patients. Both carriers and non‐carriers. Mupirocin: 95 carriers. Placebo: 86 carriers. No significant difference between both groups.
Interventions	Mupirocin or placebo. Twice daily from the day of admission (day before surgery) to the hospital until the day of surgery.
Outcomes	S. aureus infection rate.
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Low risk	Adequate
Blinding? participants	Low risk
Blinding? investigator	Low risk
Blinding? outcome assessor	Low risk
Blinding? data analysis	Low risk
Intention to treat	Low risk	reported and confirmed
Loss to follow up	High risk