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. 2008 Oct 8;2008(4):CD006216. doi: 10.1002/14651858.CD006216.pub2

Konvalinka 2006.

Methods Double‐blind, randomised controlled trial
Participants Elective cardiac surgery patients. All carriers. Mupirocin: 130. Placebo: 127. Only COPD was more prevalent in the mupirocin group (p<0.01)
Interventions Mupirocin or placebo. Twice daily for 7 days, before surgery.
Outcomes S. aureus infection rate. Mortality. Adverse events. Infection rate caused by other micro‐organisms than S. aureus.
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Low risk Adequate
Blinding? 
 participants Low risk  
Blinding? 
 investigator Low risk  
Blinding? 
 outcome assessor Low risk  
Blinding? 
 data analysis Low risk  
Intention to treat Low risk reported and confirmed
Loss to follow up High risk