Wertheim 2004b.

Methods	Double‐blind, randomised controlled trial
Participants	Nonsurgical patients. All carriers. Mupirocin: 793. Placebo: 809. No significant difference between both groups.
Interventions	Mupirocin or placebo. Twice daily for 5 days, started 1 to 3 days after admission.
Outcomes	S. aureus infection rate. Time to infection. Mortality. Adverse events.
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Low risk	Adequate
Blinding? participants	Low risk
Blinding? investigator	Low risk
Blinding? outcome assessor	Low risk
Blinding? data analysis	Low risk
Intention to treat	Low risk	reported and confirmed
Loss to follow up	Low risk	Mupirocin: 9.7 Placebo:8.3