. 2022 Mar 24;9:820799. doi: 10.3389/fnut.2022.820799

Table 1.

Different expressed metabolites in feces of each group in positive ion mode.

Group	MS2 name	MS2 score	VIP	P-value	Fold change	Changing trend
NT-free group compared with NT intervention group	Choline	1.000	1.219	0.000	0.389	↓^**
	Ornithine	0.999	1.213	0.019	10.019	↑^*
	D-Proline	0.998	1.161	0.016	4.114	↑^*
	L-Lysine	0.998	1.111	0.020	2.898	↑^*
	Deoxyadenosine	0.993	1.038	0.000	0.156	↓^**
	L-Methionine	0.989	1.036	0.002	1.804	↑^**
	Urocanic acid	0.987	1.130	0.019	0.248	↓^*
	Riboflavin	0.983	1.070	0.004	0.348	↓^**
	3-Methylhistidine	0.964	1.022	0.034	0.224	↓^*
	Anserine	0.963	1.237	0.003	0.138	↓^**
	Pyridoxine	0.960	1.364	0.000	0.022	↓^**
	Hexanoylglycine	0.958	1.192	0.012	0.137	↓^*
	Pyridoxal	0.950	1.304	0.000	0.327	↓^**
	L-Arginine	0.948	1.212	0.001	3.846	↑^**
	5-Hydroxyindoleacetic acid	0.940	1.330	0.002	0.044	↓^**
	Adenosine	0.939	1.095	0.000	0.055	↓^**
	Trigonelline	0.937	1.307	0.000	0.274	↓^**
	4-Pyridoxic acid	0.910	1.177	0.000	0.132	↓^**
	Methyldopa	0.891	1.330	0.000	0.204	↓^**
	5,6-Dihydroxyindole	0.818	1.286	0.000	0.071	↓^**
	N-Acetylleucine	0.817	1.138	0.001	0.434	↓^**
	Lutein	0.807	1.322	0.000	0.109	↓^**
	Indole	0.803	1.352	0.000	5.709	↑^**
	Methylimidazole acetaldehyde	0.749	1.210	0.000	3.342	↑^**
	Imidazole-4-acetaldehyde	0.744	1.163	0.000	0.353	↓^**
	Linoleic acid	0.638	1.248	0.000	4.456	↑^**
	Formiminoglutamic acid	0.510	1.334	0.001	0.177	↓^**
	13S-hydroxyoctadecadienoic acid	0.409	1.256	0.005	9.038	↑^**
Basal diet group compared with NT intervention group	2-Fucosyllactose	0.995	1.637	0.035	0.485	↓^*
	1-Methylhistamine	0.978	1.504	0.030	0.540	↓^*
	L-Proline	0.977	1.818	0.009	0.622	↓^**
	Pyridoxal	0.950	1.886	0.002	0.639	↓^**
	Thymine	0.928	1.391	0.041	0.684	↓^*
	Methyldopa	0.891	2.225	0.000	2.854	↑^**
	6,7-Dihydro-5-methyl-5H-cyclopenta[b]pyrazine	0.870	1.364	0.050	0.576	↓^*
	4-Hydroxy-2-butenoic acid gamma-lactone	0.836	1.241	0.011	0.380	↓^**
	Pyridoxal 5'-phosphate	0.822	2.160	0.000	0.191	↓^**
Basal diet group compared with model control group	Deoxyguanosine	0.997	1.542	0.044	1.801	↑^*
	Kynurenic acid	0.984	1.142	0.050	1.678	↑^*
	Riboflavin	0.983	1.824	0.026	0.537	↓^*
	L-Cyclo(alanylglycyl)	0.952	1.946	0.039	1.805	↑^*
	Diethanolamine	0.945	1.848	0.037	3.572	↑^*
	Cholesterol	0.915	1.315	0.041	0.593	↓^*
	L-Threo-3-Phenylserine	0.836	1.554	0.036	1.590	↑^*
	4-Hydroxy-2-butenoic acid gamma-lactone	0.836	1.958	0.030	467.029	↑^*
	4-Aminohippuric acid	0.822	1.758	0.027	1.738	↑^*
	Serotonin	0.822	1.940	0.017	1.988	↑^*
	Dihydrotestosterone	0.527	1.983	0.040	2.843	↑^*

In the table, MS2 name: the name of the substance obtained from the secondary mass spectrometry qualitative matching analysis; MS2 score: the score of the secondary matching.

Significant difference;

^**

extremely significant difference.