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. Author manuscript; available in PMC: 2022 Apr 7.
Published in final edited form as: Adv Exp Med Biol. 2021;1322:115–138. doi: 10.1007/978-981-16-0267-2_5

Table 5.8.

Antisense molecules in development

Drug Route Company Clinical trial phase ClinicalTrials.gov identifier
GSK 3228836 /IONIS-HBVRx/ISIS505358 Parenteral (SC) [67] Ionis with GSK, USA 2a NCT04449029/NCT02981602
GSK3389404/Ionis-HBV-LRx Parenteral (SC) Ionis with GSK 2a NCT02647281
RO7062931 Parenteral (SC) Roche 1a NCT03505190/NCT03038113