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. 2022 Apr 7;59(4):2100972. doi: 10.1183/13993003.00972-2021

TABLE 2.

Area under the curve (AUC) forced expiratory volume in 1 s (FEV1) at day 14

Navafenterol versus placebo Navafenterol versus UMEC/VI
FEV1 AUC LS mean difference, L (95% CI) p-value FEV1 AUC LS mean difference, L (95% CI) p-value
0–4 h 0.376 (0.320–0.432) <0.0001 0.062 (0.006–0.117) 0.0308
0–8 h 0.328 (0.271–0.385) <0.0001 0.020 (−0.037–0.077) 0.4948
0–12 h 0.296 (0.242–0.349) <0.0001 0.001 (−0.053–0.054) 0.9827
0–24 h 0.244 (0.194–0.294) <0.0001 −0.030 (−0.079–0.020) 0.2426

UMEC/VI: umeclidinium/vilanterol; LS: least-squares.