TABLE 3.
Compound | Conc of compound | % Intracellular K+a | Concn of compound (μg/ml) | % Human RBC lysis at:
|
|
---|---|---|---|---|---|
2 h | 24 h | ||||
3 | 16 μg/ml | 73 | 16 | 1 | 1 |
128 | 6 | 98 | |||
4 | NDb | 16 | 1 | 1 | |
128 | 13 | 76 | |||
5 | 4 μg/ml | 18 | 16 | 10 | 34 |
128 | 50 | 83 | |||
6 | 32 μg/ml | 39 | 16 | 4 | 1 |
128 | 50 | 100 | |||
Polymyxin B | 16 μg/ml | 25 | ND | ND | |
Water | 1.28% | 100 | ND | ND | |
Amphotericin B | ND | 1 | 11 | 39 | |
ND | 8 | 94 | 97 | ||
DMSOc | ND | 0.5 | 0 | 3 |
Relative to the level for the untreated control.
Relative to the level for the untreated control.
DMSO, dimethyl sulfoxide.