Skip to main content
. 2000 Jun;44(6):1418–1427. doi: 10.1128/aac.44.6.1418-1427.2000

TABLE 3.

The effects of selected compounds on membrane integrity in an imp mutant E. coli strain and human RBCs

Compound Conc of compound % Intracellular K+a Concn of compound (μg/ml) % Human RBC lysis at:
2 h 24 h
3 16 μg/ml 73 16 1 1
128 6 98
4  NDb 16 1 1
128 13 76
5 4 μg/ml 18 16 10 34
128 50 83
6 32 μg/ml 39 16 4 1
128 50 100
Polymyxin B 16 μg/ml 25 ND ND
Water 1.28% 100 ND ND
Amphotericin B ND 1 11 39
ND 8 94 97
DMSOc ND 0.5 0 3
a

Relative to the level for the untreated control. 

b

Relative to the level for the untreated control. 

c

DMSO, dimethyl sulfoxide.