Skip to main content
. 2022 Apr 7;45(4):205–228. doi: 10.1007/s12272-022-01378-2

Table 3.

Pharmacokinetic properties of RA calculated through pkCSM web tool

Absorption Distribution Metabolism Excretion Toxicity
GI absorption Skin Permeability (log Kp) BBB/CNS permeability CYP2D6 substrate/inhibitor Clearance (log ml/min/kg) Renal OCT2 substrate AMES Hepatotoxicity
Low  − 2.73 No No 0.25 No No No