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. 2007 Jan 24;2007(1):CD002835. doi: 10.1002/14651858.CD002835.pub3

Comparison 1. Two drugs vs three drugs.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Adverse events 3 1717 Odds Ratio (M‐H, Fixed, 95% CI) 1.75 [1.41, 2.17]
2 Discontinuation 3 1717 Odds Ratio (M‐H, Fixed, 95% CI) 1.21 [0.94, 1.55]