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. 2007 Jan 24;2007(1):CD002835. doi: 10.1002/14651858.CD002835.pub3

Puro 2005.

Methods Longitudinal open study conducted by prospective collection of data in the National registry of PEP. Subjects received either two NRTIs or two NRTIs plus a PI. Subjects who dropped out of the study as well as those who withdrew or discontinued PEP because the source person tested HIV negative were excluded. Discontinuation of PEP was defined as duration of PEP less than 28 days. Adverse events were not defined and methods for measuring adverse events were not reported.
Participants Health care workers and other persons consenting to be treated with post exposure prophylaxis post exposure to HIV ‐ 356 subjects who were prescribed two NRTIs with 915 subjects receiving two NRTIs plus a PI
Interventions Those receiving two NRTIs were compared to those receiving two NRTIs plus a PI
Outcomes Adverse events 
 Discontinuation rates
Notes Setting: Italy