Figure 2.

Lower androgen receptor (AR) expression in airways is associated with increased odds of asthma in both sexes. Odds ratios (ORs) with 95% CIs for having disease status asthma among individuals in the bottom 50% vs the top 50% of normalized AR expression in the pooled data set of bronchial epithelial samples. ORs and associated CIs and P values were determined using binomial logistic regression of [disease status equals asthma] against [normalized AR expression is less than median normalized AR expression], performed in R under RStudio. For all 3 comparisons, P is less than .001.