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. 2022 Mar 24;3:840328. doi: 10.3389/fpain.2022.840328

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Copyright © 2022 Zhang and Furst.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Possible PAG connections based on DTI from Linnman et al. (84) and Zhang et al. (76). ACC, anterior cingulate cortex; Cerebell, cerebellum; dmPFC, dorsomedial prefrontal cortex; vmPFC, ventromedial prefrontal cortex; vlPFC, ventrolateral prefrontal cortex; WM, white matter; VTA, ventral tegmental area; SN, substantia nigra; RN, red nucleus; PAG, periaqueductal gray matter; LC, locus coeruleus; ML, medial lemniscus; Dent. Nc., dentate nucleus; STT, spinothalamic tract; NST, nigrostriatal tract; MFT, medial forebrain tract; DLF, dorsal longitudinal fasciculus; SCP, superior cerebellar peduncle; MLF, medial longitudinal fasciculus.