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. 2022 Apr 7;17(4):e0266111. doi: 10.1371/journal.pone.0266111

Fig 4. The statistics of donors and samples collected in five collaborating hospitals; status as of May 12, 2021.

Fig 4

(A) The total number of donors with compulsory set of samples (as described in Materials and Methods-section and shown in Figs 1 and 2). (B) The sum of all samples collected from recruited donors. The numbers for donors and samples are divided for six different cancer diagnoses and controls (*). The control (*) category represents a healthy male cohort ≥ 65-year-old recruited as controls for patients with prostate- and colorectal cancer, used in the Loss of Y Chromosome (LOY) project. (C–F) show distribution of diagnoses according to International Classification of Diseases (ICD-10, World Health Organization) for breast, colorectal, bladder and pancreatic cancer patients, respectively. Abbreviations: C50, Malignant neoplasm of breast; C50.0, Nipple and areola; C50.1, Central portion of breast; C50.2, Upper-inner quadrant of breast; C50.3, Lower-inner quadrant of breast; C50.4, Upper-outer quadrant of breast; C50.5, Lower-outer quadrant of breast; C50.6, Axillary tail of breast; C50.8, Overlapping lesion of breast; C50.9, Breast, unspecified; C18, Malignant neoplasm of colon; C18.0, Caecum, Ileocaecal valve; C18.1, Appendix; C18.2, Ascending colon; C18.3, Hepatic flexure; C18.4, Transverse colon; C18.5, Splenic flexure; C18.6, Descending colon; C18.7, Sigmoid colon, Sigmoid (flexure); C18.8, Overlapping lesion of colon;C18.9, Colon, unspecified, Large intestine, unspecified; C19, Malignant neoplasm of rectosigmoid junction, including colon with rectum, rectosigmoid colon; C20, Malignant neoplasm of rectum, Including rectal ampulla; C21, Malignant neoplasm of anus and anal canal; C21.0, Anus, unspecified, excluding anal margin and perianal skin; C21.1, Anal canal, Anal sphincter; C67, Malignant neoplasm of bladder; C67.0, Trigone of bladder; C67.2, Lateral wall of bladder; C67.3, Anterior wall of bladder; C67.4, Posterior wall of bladder; C67.5, Bladder neck, Internal urethral orifice; C67.7, Urachus; C67.8, Overlapping lesion of bladder; C67.9, Bladder, unspecified; C25, Malignant neoplasm of pancreas; C25.0, Head of pancreas; C25.1, Body of pancreas; C25.2, Tail of pancreas. ND–not yet defined due to temporary lack of medical documentation.