TABLE 1.
MICs for K. pneumoniae strains with different resistance phenotypes and their transconjugantsa
| Resistance phenotype group | No. of clinical isolates | MIC (μg/ml) of drug for clinical isolates
|
No. of transconjugants | MIC (μg/ml) of drug for transconjugants
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AMP | AMC | CAZ | CTX | FOX | IPM | AMP | AMC | CAZ | CTX | FOX | IPM | |||
| I | 14 | >256 | 4–8 | ≥256 | 3–16 | 3–16 | 0.125–0.25 | 11 | >256 | 4–8 | ≥256 | 6–16 | 2–6 | 0.125–0.25 |
| II | 2 | >256 | 4–8 | 2–24 | 128–256 | 8–16 | 0.125 | 2 | >256 | 4–8 | 2–3 | 128–256 | 8–16 | 0.125 |
| III | 3 | >256 | 16 | 96 | >256 | >256 | 0.25–0.5 | 3 | >256 | 24 | 32–64 | >256 | >256 | 0.25–0.5 |
| IV | 1 | >256 | 12 | >256 | 48 | >256 | 0.5 | 1 | >256 | 12 | >256 | 8 | >256 | 0.125 |
a
MICs were determined by the E test. Abbreviations: AMP, ampicillin; AMC, amoxicillin-clavulanic acid combination, CAZ, ceftazidime; CTX, cefotaxime; FOX, cefoxitin; IPM, imipenem.