TABLE 2.
Pool | Targets in mix | LDT |
QIAstat-Dx RP2.0 |
BioFire RP2.1 |
Ct value | Ct value | Detected | ||
1 | Parainfluenza virus 1 | 16.6 | 21.5 | Detected |
Parainfluenza virus 2 | 25.0 | ND | Detected | |
Parainfluenza virus 3 | 26.0 | ND | Detected | |
Parainfluenza virus 4 | 28.7 | ND | Detected | |
2 | Influenza A virus H1N1 | 31.4 | 32.0 | Detected |
Influenza B virus (Victoria) | 31.4 | 35.6 | Detected | |
Respiratory syncytial virus A | 32.1 | 31.6 | Detected | |
SARS-CoV-2 | 26.5 | 33.5 | Detected | |
3 | Coronavirus OC43 | 27.0 | 28.6 | Detected |
Coronavirus 229E | 24.8 | 28.8 | Detected | |
Coronavirus NL63 | 24.6 | 28.9 | Detected | |
Coronavirus HKU1 | 26.4 | 32.3 | Detected | |
4 | Rhinovirus 5 | 21.2 | 31.2 | Detected |
Enterovirus D68 | 25.3 | 31.2 | Detected | |
Adenovirus 1 | 30.3 | 34.9 | Detected | |
5 | Mycoplasma pneumoniae | N/A | 28.3 | Detected |
Legionella pneumoniae* | N/A | 30.8 | N/A | |
Bordetella pertussis | N/A | 29.3 | Detected |
LDT, laboratory developed test (respiratory screen); Ct, cycle threshold; ND, not detected; N/A, not applicable. *The Legionella pneumonia target is not currently present in BioFire RP2.1. Pool 5 could not be directly compared as the bacterial targets are not present in the LDT respiratory screen.