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. 2022 Feb 26;4(1):vdac025. doi: 10.1093/noajnl/vdac025

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© The Author(s) 2022. Published by Oxford University Press, the Society for Neuro-Oncology and the European Association of Neuro-Oncology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — Kaplan-Meier estimates of PFS, with insets demonstrating the number of events and median PFS. (A) PFS in cohort 1c (nivolumab + RT + TMZ, methylated/unknown or unmethylated MGMT promoter) and cohort 1d (nivolumab + RT, unmethylated MGMT promoter) in part A and in cohort 1c (nivolumab + RT + TMZ, unmethylated MGMT promoter) and cohort 1d (nivolumab + RT, unmethylated MGMT promoter) in part B. (B) PFS in cohort 1c in part A (nivolumab + RT + TMZ, methylated/unknown MGMT promoter; nivolumab + RT + TMZ, unmethylated MGMT promoter). Symbols indicate censored observations. Abbreviations: meth, methylated; MGMT, O⁶-methylguanine-DNA methyltransferase; NE, not estimable; PFS, progression-free survival; RT, radiotherapy; TMZ, temozolomide; unk, unknown; unmeth, unmethylated.