TABLE 1.
Characteristics of the strains of C. meningosepticum used in this studya
| Designation | Yr | Country of originb | MIC (μg/ml) of:
|
blaB detection by:
|
blaB3 detection by:
|
blaACME detection by PCR | blaCME-2 detection by PCR | pI(s) of β-lactamase(s) | Sp act (μmol/min/mg of protein)
|
||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Imipenem | Meropenem | PCR | Probe | PCR | Probe | Imipenem | Cephaloridine | ||||||
| 97/P/5448 | 1997 | UK | >32 | >32 | + | + | − | − | + | + | 7.7, 8.2, 8.6, 8.9 | 0.53 | 0.17 |
| NCTC 10016T | 1958 | USA | 32 | 16 | − | − | + | + | − | − | 8.9 | 0.16 | 0.23 |
| NCTC 10585 | 1950 | USA | >32 | >32 | + | + | − | − | + | + | 7.1, 8.6 | 0.52 | 0.15 |
| NCTC 10586 | 1956 | USA | >32 | >32 | + | + | − | − | + | + | 8.6 | 0.43 | 0.14 |
| NCTC 10587 | 1961 | Ceylon | >32 | >32 | + | + | − | − | + | + | 7.1, 8.6 | 0.53 | 0.20 |
| NCTC 10588 | 1962 | USA | >32 | 16 | + | + | − | − | + | + | 7.7 | 0.39 | 0.07 |
| NCTC 10589 | 1962 | USA | 32 | 32 | − | + | − | − | + | + | 6.2 | 0.37 | 0.09 |
| NCTC 11305 | 1979 | France | >32 | >32 | − | − | − | − | + | + | 6.5, 7.7 | 0.36 | 0.09 |
| NCTC 11306 | 1979 | France | >32 | >32 | − | − | − | − | − | + | 7.1, 7.5, 7.9 | 0.23 | 0.19 |
| NCTC 11307 | 1979 | France | 4 | 2 | − | − | − | − | − | − | 8.2 | 0.66 | 0.01 |
| NCTC 11308 | 1979 | France | 4 | 8 | − | − | − | − | − | − | 7.6 | 0.18 | 0.01 |
| NCTC 11309 | 1979 | France | 32 | >32 | + | + | − | − | + | + | 8.2, 8.6 | 0.42 | 0.11 |
| NCTC 11310 | 1979 | France | 4 | 4 | − | − | − | − | − | − | 5.7, 6.2 | 0.09 | <0.01 |
| NCTC 11379 | 1980 | France | >32 | >32 | − | − | − | − | + | − | 7.1, 8.2, 8.6 | 0.04 | 0.18 |
| NCTC 11380 | 1980 | France | 2 | 4 | − | − | − | − | − | − | 5.7, 6.1 | 0.12 | 0.01 |
| NCTC 11381 | 1980 | France | >32 | 8 | − | − | + | + | − | − | 8.8, 9.1 | 0.20 | 0.01 |
a
PCR and probe results are presented as positive (+) or negative (−).
b
Abbreviations: UK, United Kingdom; USA, United States of America.