Table 4.

Antinociceptive activity of H. plantaginea assessed using the hot plate test.

Treatment	Dose (mg/kg)	Latency time in seconds (mean ± SEM)
		After 30 min	After 60 min	After 90 min
Normal saline	10 ml/kg	9.03 ± 0.40	10.05 ± 0.30	8.67 ± 0.65
Standard	5 mg/kg	17.23 ± 0.33∗∗∗	19.56 ± 0.52∗∗∗	13.27 ± 0.25∗∗∗
Hp. Chf	100 mg/kg	14.33 ± 0.44∗∗	16.17 ± 0.42∗∗	11.25 ± 0.52∗∗
Hp. EtAc	100 mg/kg	12.83 ± 0.52∗	14.00 ± 0.10∗∗∗	8.83 ± 0.80∗

The data represent analgesic activities through hot plate test in mice. The data were expressed as means ± SEM (n = 6) analyzed via two-way ANOVA followed by Bonferroni's posttest. ^∗P < 0.05; ^∗∗P < 0.01; ^∗∗∗P < 0.001; and ns: not significant.