Table 5.
Summary of continuous measures for hypertensive patients assigned to metoprolol at 50 mg BID. P values of the paired analysis of continuous data with a nonparametric Wilcoxon test for comparison of results before and after the six-week treatment.
| Parameter | Median v1 (Q1–Q3) | Median v2 (Q1–Q3) | P |
|---|---|---|---|
| DTHR (beats/min) | 81.11 (77.02–89.21) | 68.36 (65.93–73.73) | <0.0001 |
| DTSBP (mmHg) | 149.14 (143.49–156.49) | 138.18 (128.65–144.28) | 0.001 |
| DTDBP (mmHg) | 89.21 (84.26–92.83) | 82.29 (74.88–84.93) | 0.0017 |
| NTHR (beats/min) | 64.04 (60.76–67.59) | 57.61 (53.02–63.46) | 0.0003 |
| NTSBP (mmHg) | 130.76 (120.71–137.34) | 114.65 (107.48–123.16) | 0.0003 |
| NTDBP (mmHg) | 73.63 (68.52–81.62) | 62.42 (58.17–69.15) | 0.0013 |
| 24-hHR (beats/min) | 77.74 (74.06–83.78) | 67.13 (63.82–70.69) | <0.0001 |
| 24-hSBP (mmHg) | 144.73 (141.09–150.52) | 133.88 (125.23–138.88) | 0.0004 |
| 24-hDBP (mmHg) | 83.86 (81.57–90.38) | 79.24 (71.47–81.98) | 0.0008 |
| Bmean (kFU) | 698.78 (508.65–847.20) | 841.20 (614.19–950.31) | 0.0034 |
| FImax (kFU) | 762.31 (545.56–901.12) | 900.81 (658.66–1046.42) | 0.0034 |
| FRmin (kFU) | 578.17 (425.36–715.79) | 674.15 (508.32–804.51) | 0.0052 |
| Imax (kFU) | 43.59 (38.66–72.42) | 53.08 (35.33–109.49) | 0.9799 |
| Rmin (kFU) | 108.34 (70.17–143.78) | 139.98 (103.53–168.55) | 0.0214 |
| IRampl (kFU) | 149.88 (104.86–223.99) | 188.66 (150.42–264.23) | 0.0182 |
| CImax | 0.32 (0.29–0.38) | 0.34 (0.23–0.41) | 0.2312 |
Bmean, mean fluorescence recorded before ischemia as the baseline value; FImax, the maximal fluorescence above the baseline during ischemia; FRmin, the minimal fluorescence below the baseline during reperfusion; Imax, the difference between FImax and Bmean; IRampl, the difference between FImax and FRmin; Rmin, the difference between Bmean and FRmin; CImax, Imax/IRampl rate; 24-hSBP, 24-hour systolic blood pressure; 24-hDBP, 24-hour diastolic blood pressure; 24-hPR, 24-hour pulse rate; DTSBP, day time systolic blood pressure; DTDBP, day time diastolic blood pressure; DTPR, day time pulse rate; NTSBP, night time systolic blood pressure; NTDBP, night time diastolic blood pressure; and NTPR, night time pulse rate.