Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Stress leads to a damage of endothelial cells (brown), including brain-region specific downregulation of the tight junction protein claudin-5 (inset) resulting in increased permeability of the BBB and infiltration of peripheral factors such as cytokines.
