Figure 5.

Time-Restricted Feeding Disrupts Body Temperature Rhythms. (A) Inactive phase fed mice demonstrated a significant increase in body temperature rhythms immediately prior to lights off, and a significant reduction in activity during most of the dark phase relative to both groups. (B) Inactive phase fed mice displayed increased body temperature range relative to all other groups. Error bars represent SEM; @ main effect of day, & main effect of timing of food intake, $ timing of food intake by day interaction; (A) two-way RM ANOVA (B) one-way ANOVA; Fisher’s LSD multiple comparisons test. # inactive phase vs active phase at p < 0.05. * ad libitum vs inactive phase at p<0.05. ~ ad libitum vs active phase at p<0.05. Graph bars that do not share a letter are statistically significant different at p < 0.05. n=5–6 per group.