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. 2022 Apr 8;209:114222. doi: 10.1016/j.bios.2022.114222

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Fig. 4 — Data from tests of sensitivity, selectivity, and linearity range of the prepared biological sensors. (A) Study of the optimal response - incubation of the electrode in a protein N solution for different periods. (B) Dependence of the responses of various sensors (Au, BDD, GC) versus concentrations of Wuhan-N protein (RNA binding domain of nucleocapsid protein of Wuhan strain of SARS-CoV-2). (C) Cross-reactivity with other human upper respiratory tract viruses. Selectivity of different types of electrodes was tested for inactivated viruses. Epstein-Barr virus (EBV), respiratory syncytial virus (RSV), influenza A virus H1N1 Virginia 3 subtype (H1N1v3), PBS/TBS buffer, recombinant N protein from a different human coronavirus (HCoV-NL63) served as a negative control, and swabs from COVID-19 positive patients served as a positive sample.