. Author manuscript; available in PMC: 2023 Aug 1.

Published in final edited form as: Int J Gynaecol Obstet. 2021 Oct 31;158(2):398–405. doi: 10.1002/ijgo.13972

TABLE 2.

Correlation between pre-delivery angiogenic factors and the daily verbal numeric rating score of pain

Angiogenic factor	Daily verbal numeric rating score (VNRS) of pain	Spearman’s correlation
		Normotensive, n = 90		sPE, n = 50
		Correlation coefficient	P value	Correlation coefficient	P value
sFlt-1
	Pre-delivery	+0.188	0.076	−0.035	0.811
	Postpartum day 0	−0.108	0.309	−0.075	0.608
	Postpartum day 1	−0.056	0.606	−0.231	0.110
	Postpartum day 2	+0.067	0.541	−0.342	0.017^a
	Postpartum day 3	−0.173	0.230	−0.465	0.003^a

PIGF
	Pre-delivery	−0.164	0.124	+0.015	0.918
	Postpartum day 0	+0.053	0.618	−0.027	0.854
	Postpartum day 1	−0.092	0.392	+0.140	0.339
	Postpartum day 2	−0.025	0.816	+0.169	0.251
	Postpartum day 3	+0.236	0.098	+0.124	0.453

sFlt-1/PIGF ratio
	Pre-delivery	+0.173	0.104	−0.054	0.707
	Postpartum day 0	−0.102	0.337	−0.035	0.812
	Postpartum day 1	+0.043	0.693	−0.231	0.110
	Postpartum day 2	+0.059	0.589	−0.303	0.037^a
	Postpartum day 3	−0.248	0.082	−0.293	0.070

Abbreviation: PIGF, placental growth factor (PIGF); sPE, Pre-eclampsia with severe features; sFlt-1, Soluble fms-like tyrosine kinase-1.

Significant p-value.