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Characteristics of potential blood biomarkers for CID in ROC analysis.
| AUC | Cut-off (pg/mL) | Sensitivity | Specificity | 95% CI | |
|---|---|---|---|---|---|
| AQP4 | 0.726 | ≤ 2109.7 | 0.711 | 0.625 | (0.618, 0.833) |
| CX43 | 0.772 | ≤ 2542.7 | 0.816 | 0.719 | (0.668, 0.876) |
| CX30 | 0.823 | ≤ 6348.5 | 0.776 | 0.781 | (0.733, 0.914) |
AQP4, aquaporin-4; AUC, area under the curve; CI, confidence interval; CID, chronic insomnia disorder; CX30, connexin 30; CX43, connexin 43; ROC, receiver operating characteristic.
