TABLE 1.
Clinical characteristics of PD hypertensive patients with or without aTRH
Characteristics | Overall | Non‐aTRH | aTHR | P‐Value a |
N | 1789 | 1034 | 755 | – |
Male (n [%]) | 949 (53.0) | 505 (48.8) | 444 (58.8) | <0.001 |
Age (years) | 49.8 ± 13.5 | 50.8 ± 13.8 | 48.4 ± 13.0 | <0.001 |
BMI (kg/m2) | 22.7 ± 3.6 | 22.5 ± 3.7 | 23.0 ± 3.4 | 0.002 |
Diabetes (n [%]) | 346 (19.3) | 204 (19.7) | 142 (18.8) | 0.626 |
Smoker (n [%]) | 286 (17.0) | 144 (14.8) | 142 (19.9) | 0.005 |
Drinker (n [%]) | 153 (9.1) | 77 (7.9) | 76 (10.7) | 0.051 |
With RRF (n [%]) | 1124 (64.0) | 675 (66.4) | 449 (60.8) | 0.014 |
Home SBP (mmHg) | 141.1 ± 16.0 | 136.7 ± 14.9 | 147.3 ± 15.2 | <0.001 |
Home DBP (mmHg) | 86.7 ± 10.9 | 84.8 ± 10.4 | 89.1 ± 11.1 | <0.001 |
Office SBP (mmHg) | 143.4 ± 18.2 | 139.0 ± 17.3 | 149.3 ± 17.6 | <0.001 |
Office DBP (mmHg) | 87.2 ± 12.6 | 85.7 ± 11.8 | 89.4 ± 13.3 | <0.001 |
Lab examinations | ||||
Serum creatinine (mg/dl) | 11.2 ± 3.4 | 10.8 ± 3.4 | 11.8 ± 3.3 | <0.001 |
Serum albumin (g/dl) | 3.6 ± 0.5 | 3.7 ± 0.5 | 3.6 ± 0.5 | <0.001 |
Blood hemoglobin (g/dl) | 10.5 ± 2.1 | 10.6 ± 2.0 | 10.3 ± 2.1 | 0.001 |
Baseline PD characteristics | ||||
CAPD (n [%]) | 1725 (96.4) | 997 (96.4) | 728 (96.4) | 0.998 |
PD vintage (months) | 26 (11‐50) | 24 (10‐50) | 27 (12‐48) | 0.760 |
UF volume (L/d) | 0.5 (0.2‐0.8) | 0.5 (0.2‐0.8) | 0.6 (0.3‐0.9) | <0.001 |
Urine volume (L/d) | 0.3 (0‐0.7) | 0.3 (0‐0.8) | 0.3 (0‐0.6) | 0.001 |
Dialysate GLUC (%) | 1.81 ± 0.34 | 1.79 ± 0.34 | 1.84 ± 0.34 | 0.003 |
Kt/V score | 1.95 ± 0.57 | 2.01 ± 0.57 | 1.86 ± 0.55 | <0.001 |
PET type * | 0.007 | |||
High (n [%]) | 143 (10.1) | 69 (8.5) | 74 (12.4) | – |
High average (n [%]) | 660 (46.7) | 366 (45.0) | 294 (49.2) | – |
Low average (n [%]) | 538 (38.1) | 337 (41.4) | 201 (33.6) | – |
Low (n [%]) | 71 (5.0) | 42 (5.2) | 29 (4.8) | – |
ESA dosage (1000U/week) | 7 (2.5‐10) | 6 (2‐10) | 7.8 (5‐10) | <0.001 |
Note: Data of overall patients, patients with aTRH and non‐aTRH were presented as numbers and percentages, means and standard deviations, or median and interquartile range. KT/V, and PET were calculated by formulas mentioned before. PD, peritoneal dialysis; aTRH, apparent treatment‐resistant hypertension; BMI, body mass index; RRF, Residual renal function; SBP, systolic blood pressure; DBP, diastolic blood pressure; CAPD, continuous ambulatory peritoneal dialysis; UF, ultrafiltration; GLUC, glucose concentration; PET, peritoneal equilibration test, ESA, erythropoiesis‐stimulating agents.
PET type based on 1428 PD hypertensive patients including 863 nonaTRH patients and 565 aTRH patients.
P for comparisons between aTRH and nonaTRH patients by t‐test, Kruskal–Wallis test, or Chi‐squared tests for continuous and categorical variables, respectively.