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. 2022 Feb 26;39(4):1832–1843. doi: 10.1007/s12325-022-02061-0
Clopidogrel improves microcirculation in ST-elevation myocardial infarction (STEMI) treated with fibrinolytics, when compared with placebo.
In acute coronary syndrome, ticagrelor is superior to clopidogrel in terms of hard endpoint incidences.
We analyzed the effect of ticagrelor or clopidogrel on coronary microcirculation in patients presenting with STEMI.
Despite lower platelet reactivity with ticagrelor, in comparison with clopidogrel, there is no difference between the effect of the drugs on coronary microcirculation in patients with STEMI treated with fibrinolytics.