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. 2021 Dec 13;29(18):26969–26976. doi: 10.1007/s11356-021-17608-x

Table 1.

Characteristics of lead (Pb) concentration in CIN subjects and controls (n = 133)

Research group Pb concentration (μg/dL)
Median Interquartile range
CIN (N = 40) 5.5 4.7–6.4
  CIN I (N = 6) 6.6 6.4–7.0
  CIN II (N = 6) 5.0 4.7–5.8
  CIN III (N = 28) 5.4 4.7–6.2
Control (N = 93) 4.7 4.3–5.8
  Non-cancerous/HPV infected (N = 50) 4.7 4.2–8.7
  Non-cancerous/non-HPV infected (N = 43) 4.7 4.5–5.4
Comparisons P value
CIN versus overall controls < 0.01a
CIN versus HPV infected control 0.080a
CIN versus non-HPV infected control < 0.01a
Comparison between CIN grades 0.019b

Abbreviations: CIN, cervical intraepithelial neoplasia; HPV, human papillomavirus; Pb, lead

aThe P value comparison between two indicated groups by the Mann-Whitney U test

bThe P value comparison between three groups by the Kruskal-Wallis test