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. 2022 Apr 7;117(1):21. doi: 10.1007/s00395-022-00928-5

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — ¹⁹F signaling provides additional information on initial remodeling and remote myocardial contractile function early after myocardial infarction. At comparable infarct sizes and areas at risk, increased macrophage signals delineated by ¹⁹F-CMR are associated with impaired remote myocardial contractile function and remodeling early after AMI. Representative images of two pigs after stratification for the whole heart ¹⁹F integral > / < 200 SNR × ml and border zone ¹⁹F SNR > / < 8 are shown. The edema extent (blue borders) and infarct size (green borders) were comparable. Images of LV areas in end diastole and end systole display differences in remote myocardial contractile function and ventricular shape. The ¹⁹F cut-off identifies pigs with impaired remote wall thickening and larger end diastolic volume index (EDVi).