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. 2022 Apr 7;13:1891. doi: 10.1038/s41467-022-29413-2

Fig. 4. Co-crystal structures of GC376 analogs with SARS-CoV-2 3CL protease.

Fig. 4

a The co-crystal structure of 3CL-EB46 complex. b The co-crystal structure of 3CL-EB48 complex. c The co-crystal structure of 3CL-SL-4-241 complex. d The co-crystal structure of 3CL-NK01-14 complex. e The co-crystal structure of 3CL-NK01-63 complex. f The co-crystal structure of 3CL-EB54 complex. g The co-crystal structure of 3CL-NK01-48 complex. h The co-crystal structure of 3CL-EB56 complex. i Alignment of the co-crystal structure of 3CL-EB46, 3CL-EB48, 3CL-EB54, 3CL-EB56, 3CL-SL4-241, 3CL-NK01-14, 3CL-NK01-48, 3CL-NK01-63, and 3CL-GC376 complex.