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. 2022 Mar 24;34(2):152–153. doi: 10.5021/ad.2022.34.2.152

Table 1. Differential diagnoses of epidermal cyst en plaque.

Contents Epidermal cyst MEP3 Idiopathic calcinosis cutis2 Steatocystoma multiplex4
Peak age Third and fourth decades Fourth to seventh decades Third and fourth decades Second and third decades
Clinical features Flesh colored nodule Firm, white papules (several millimeters) on an erythematous base Slow-growing yellowish nodules Firm, yellowish colored papules and nodules
Histology Lined by stratified squamous cells with keratinous and other materials Lined by stratified squamous cells with keratinous materials Deposition of calcium in the dermis without lining Lined by stratified squamous epithelium containing sebaceous gland
Predilection site Scalp, Trunk, Face Retroauricular area Scrotum Chest
Lesion numbers Single to multiple Multiple Single to multiple Multiple
Treatment options Excision Excision
Topical retinoids
Excision Excision
Laser treatment

MEP: milia en plaque.