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. 2022 Mar 31;106(7):2433–2444. doi: 10.1007/s00253-022-11888-0

Table 2.

In vitro antiplasmodial activity of artemisinin (1) and its biotransformed products

Compound Antiplasmodial activity
Yes/No
IC50 (ng/mL)
1 Yes 28.07 (95% CI 27.07–29.09)
1 and 4 (1:1) Yes 46.36 (95% CI 44.52–48.27)
2 No  > 50,800
3 No 25,643 (95% CI 22,395 to 29,362)
5 No  > 53,200