Fig. 3.

Cost-effectiveness acceptability curve for bivalent, quadrivalent, and nonavalent HPV vaccination. In this graph, the cost-effectiveness acceptability curve maps the probability a certain vaccination strategy is preferred over others in South Africa across varying WTP ratios. The red line represents the bivalent vaccination strategy, the orange line represents the quadrivalent vaccination strategy, and the blue line represents the nonavalent vaccination strategy. At the South African WTP threshold of R23,630 per QALY, nonavalent vaccination is the preferred strategy, with a probability of 90.2%. HPV human papillomavirus, QALYs quality-adjusted life-years, WTP willingness to pay, R South African Rand