TABLE 3.
Overall and subgroup analysis results regarding the effects of Traditional Chinese Exercises on cognition function.
| Outcomes | Overall and Subgroup analysis | No. of studies | SMD (95%CI) | P-value | Test of heterogeneity |
||
| χ2 | P-value | I2 (%) | |||||
| Global cognition function | Overall | 7 | 0.32 (0.18, 0.47) | <0.001 | 5.21 | 0.517 | 0 |
| TCEs vs. Active control | 6 | 0.29 (0.15, 0.44) | <0.001 | 3.60 | 0.608 | 0 | |
| TCEs vs. Inactive control | 3 | 0.58 (0.21, 0.94) | 0.002 | 0.29 | 0.867 | 0 | |
| Tai Chi | 4 | 0.36 (0.15, 0.56) | 0.001 | 4.17 | 0.243 | 28.1 | |
| Qigong | 3 | 0.33 (−0.04, 0.70) | 0.077 | 1.04 | 0.595 | 0 | |
| <24 weeks | 4 | 0.35 (0.06, 0.64) | 0.017 | 4.53 | 0.210 | 33.8 | |
| ≥24 weeks | 3 | 0.38 (0.16, 0.61) | 0.001 | 0.23 | 0.890 | 0 | |
| Educational level < 6 years | 3 | 0.31 (0.12, 0.51) | 0.002 | 2.61 | 0.271 | 23.5 | |
| Educational level ≥ 6 years | 4 | 0.43 (0.12, 0.74) | 0.007 | 2.05 | 0.563 | 0 | |
| Group practices | 5 | 0.49 (0.21, 0.77) | 0.001 | 2.68 | 0.613 | 0 | |
| Group and Home practices | 2 | 0.27 (0.10, 0.43) | 0.001 | 0.79 | 0.375 | 0 | |
| Petersen diagnostic criteria | 5 | 0.32 (0.17, 0.47) | <0.001 | 3.11 | 0.539 | 0 | |
| Neuropsychological test diagnostic criteria | 2 | 0.39 (−0.23, 1.02) | 0.214 | 2.00 | 0.158 | 49.9 | |
| Short-term memory function | Overall | 6 | 0.22 (0.05, 0.39) | 0.013 | 6.13 | 0.294 | 18.4 |
| TCEs vs. Active control | 4 | 0.22 (−0.01, 0.45) | 0.056 | 5.10 | 0.165 | 41.1 | |
| TCEs vs. Inactive control | 3 | 0.28 (−0.04, 0.60) | 0.082 | 1.02 | 0.600 | 0 | |
| <24 weeks | 3 | 0.29 (0.10, 0.47) | 0.003 | 1.61 | 0.447 | 0 | |
| ≥24 weeks | 3 | 0.14 (−0.15, 0.43) | 0.342 | 2.79 | 0.248 | 28.3 | |
| Educational level < 6 years | 2 | 0.14 (−0.11, 0.38) | 0.282 | 2.23 | 0.136 | 55.1 | |
| Educational level ≥ 6 years | 4 | 0.36 (0.08, 0.64) | 0.011 | 2.19 | 0.534 | 0 | |
| Long-term memory function | Overall | 5 | 0.53 (0.20, 0.86) | 0.002 | 14.90 | 0.005 | 73.1 |
| TCEs vs. Active control | 3 | 0.27 (0.11, 0.43) | 0.001 | 1.40 | 0.496 | 0 | |
| TCEs vs. Inactive control | 3 | 0.83 (0.31, 1.34) | 0.002 | 4.73 | 0.094 | 57.8 | |
| <24 weeks | 2 | 0.42 (−0.12, 0.95) | 0.126 | 3.63 | 0.057 | 72.4 | |
| ≥24 weeks | 3 | 0.65 (0.07, 1.23) | 0.028 | 8.74 | 0.013 | 77.1 | |
| Educational level < 6 years | 2 | 0.28 (0.09.0.47) | 0.004 | 1.33 | 0.249 | 24.7 | |
| Educational level ≥ 6 years | 3 | 0.80 (0.25, 1.36) | 0.005 | 5.52 | 0.063 | 63.7 | |
| Shifting§ | Overall | 5 | −0.39 (−0.54, −0.25) | <0.001 | 2.66 | 0.615 | 0 |
| TCEs vs. Active control | 3 | −0.36 (−0.52, −0.20) | <0.001 | 1.03 | 0.596 | 0 | |
| TCEs vs. Inactive control | 2 | −0.58 (−0.96, −0.21) | 0.002 | 0.45 | 0.502 | 0 | |
| <24 weeks | 3 | −0.45 (−0.70, −0.20) | <0.001 | 2.53 | 0.283 | 20.8 | |
| ≥24 weeks | 2 | −0.38 (−0.61, −0.15) | 0.001 | 0.10 | 0.747 | 0 | |
| Educational level < 6 years | 2 | −0.34 (−0.50, −0.17) | <0.001 | 0.05 | 0.828 | 0 | |
| Educational level ≥ 6 years | 3 | −0.60 (−0.92, −0.29) | <0.001 | 0.48 | 0.785 | 0 | |
| Language ability | Overall | 3 | 0.32 (0.13, 0.51) | 0.001 | 2.56 | 0.279 | 21.7 |
| <24 weeks | 2 | 0.45 (0.00, 0.90) | 0.049 | 2.25 | 0.133 | 55.6 | |
| ≥24 weeks | 1 | 0.26 (0.00, 0.51) | 0.048 | 0 | – | 0 | |
| Visuospatial perception | Overall | 4 | 0.31 (0.15, 0.46) | <0.001 | 1.53 | 0.675 | 0 |
| TCEs vs. Active control | 2 | 0.27 (0.11, 0.44) | 0.001 | 0.49 | 0.482 | 0 | |
| TCEs vs. Inactive control | 2 | 0.48 (0.11, 0.85) | 0.012 | 0.06 | 0.804 | 0 | |
| <24 weeks | 2 | 0.27 (0.05, 0.50) | 0.017 | 1.10 | 0.295 | 8.7 | |
| ≥24 weeks | 2 | 0.36 (0.15, 0.46) | 0.002 | 0.08 | 0.773 | 0 | |
TCEs, Traditional Chinese Exercises. §Negative effect sizes of shifting indicate greater improvement induced by TCEs.