Table 2.
Number of differentially methylated CpGs in 176 genes with significant differences between ART conceived and naturally conceived newborns.
| No. of differentially methylated CpGs per gene | No. of genes | % of genes | Gene(s) |
|---|---|---|---|
| 1 | 121 | 68.8 | ADO, AFAP1, AFDN-DT, AFMID, AGBL4, AKR1B1, ALK, ANKRD26, ANKRD30A, APBA1, APOA5, ARHGAP22, ARL4A, ATP8B3, BANP, BET1, BOLA1, CACNA1H, CCSAP, COX16, CRACDL, CYB5B, EBF3, EMCN, EML1, ENPP6, ERLIN2, FANCC, FCHO1, FGF22, FIGNL1, FSCN2, FUCA1, GABRB3, GALNT9, GGN, GOPC, GPATCH1, GRB2, GTF2A1L:STON1-GTF2A1L, HOXD4, INPP5A, KCNK5, KLHL8, LBP, LILRB4, LIPE-AS1, LOC102467224, LOC440434, LOC644669, LONP2, LTN1, MAL2, MFSD14C, MIR646HG, MIR7-3, MRPL3, MRPS25, MSX1, MTOR, MYH7B, MYO1D, NABP2, NBEAL1, NDUFAF1, NPEPPS, NUP205, NUPL1, NUS1, OCA2, OR4C13, OR51A2, OR5D16, OVCH1-AS1, PACS2, PCSK7, PDE11A, PDE7B, PIM1, POLR1E, PPP1R13L, PRRG2;NOSIP, PTGR2, PTPRQ, ANKRD20A19P, RASL11B, RBPJL, RESP18, RGR, RHPN2, RPS6KA2, RPS6KC1, RPS6KC2, RYR2, SCARA5, SCG2, SLC17A7, SLC5A1, SLC9A2, SLC9B1, SMYD3, SNAP91, SNORD115-45, SPESP1, SRP19, SVIL, TBC1D12, TBC1D15, TBC1D19, TCTN1, TEX14, TOGARAM1, TSPEAR, TTC29, TXNDC12, UQCRB, USP48, WDR19, ZNF708, ZNF709, ZPBP |
| 2 | 20 | 11.4 | ATG4C, ATG5, COL9A1, DRC1, LOXL1, LUC7L, MATN4, MTERF, NLRP2, NTNG2, OXCT1, PRR23A, PRR23B, RAD54B, RFPL2, RWDD2B, TCERG1L, TSTD1, VPS51, YIF1B |
| 3 | 11 | 6.3 | ANKRD2, CDH20, EIF2B3, FAM228A, MORC2-AS1, PRSS41, RNF126P1, RPS2P32, SDHAF1, STX1, USH1G |
| 4 | 4 | 2.3 | GLI2, KLK4, SLC35F3, TMEM263 |
| 5 | 3 | 1.7 | LDHAL6A, NECAB3, PNLDC1 |
| 6 | 7 | 4.0 | APC2, C17orf98, CHRNE, GET1, MAN2B1, SNCB, SYCP1 |
| 7 | 2 | 1.1 | PRR25, ZNF727 |
| 8 | 6 | 3.4 | CCDC166, LOC650226, MTNR1B, PIWIL1, PXDNL, RBM46 |
| 9 | 0 | 0.0 | |
| 10 | 1 | 0.6 | BRCA1 |
| 11 | 1 | 0.6 | HLA-DQB2 |